منابع مشابه
Renoprotective effects of incretin‐based drugs: A novel pleiotropic effect of dipeptidyl peptidase‐4 inhibitor
Diabetic nephropathy is a leading cause of end-stage renal disease worldwide, and is a serious problem that must be addressed. Incretin-based drugs stimulate insulin secretion from pancreatic b-cells blood glucose-dependently with low risk for hypoglycemia and bodyweight gain. In addition, incretin acts on the multiple organs through the incretin receptors as well as the pancreas. Several repor...
متن کاملRenoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes.
Nox (NADPH oxidase)-derived ROS (reactive oxygen species) have been implicated in the development of diabetic nephropathy. Of the Nox isoforms in the kidney, Nox4 is important because of its renal abundance. In the present study, we tested the hypothesis that GKT136901, a Nox1/4 inhibitor, prevents the development of nephropathy in db/db (diabetic) mice. Six groups of male mice (8-week-old) wer...
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R an article published, entitled “renoprotective effect of aged garlic extract in streptozotocin-induced diabetic rats” (1). In this study, diabetic rats were feed by aged garlic juice orally. The serum and urinary biochemical parameters were analyzed in all the groups and at the end of 12 weeks follow up, the kidney morphological examination were performed, too. They found that, diabetic rats ...
متن کاملRenoprotective effects of green tea
*Corresponding author: Shabnam Hajian, Medical Plants Research Center, Shahrekord University of Medical Sciences, Sharekord, Iran. Email: [email protected] Free radicals lead to chronic diseases such as cancer, diabetes, atherosclerosis, nephrotoxicity, hepatotoxicity (1,2). Green tea (Camellia sinensis) is a popular herbal remedy worldwide. Polyphenols in green tea have attracted much atte...
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I read with great interest the article by Altın et al. (1) with reference to their experience on dabigatran treatment for acute renal infarction (ARI) in a case report entitled "A novel oral anticoagulant, dabigatran, in acute renal infarction” published in Anatol J Cardiol 2015; 15: 158-9. The authors claimed that in patients with ARI, a direct thrombin inhibitor, dabigatran, is preferred for ...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2012
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.101.1347